Cary GrantRoger O. Thornhill
Eva Marie SaintEve Kendall
James MasonPhillip Vandamm
Jessie Royce LandisClara Thornhill
Philip CoolidgeDr. Cross
Doreen LangMaggie - Thornhill's Secretary
Josephine HutchinsonVandamm's Sister aka Mrs. Townsend
Leo G. CarrollThe Professor
Philip OberLester Townsend
Adam WilliamsValerian
Edward PlattVictor Larrabee
Robert EllensteinLicht
Martin LandauLeonard
Les TremayneAuctioneer
Patrick McVeySergeant Flamm
Edward BinnsCaptain Junket
Ken LynchCharley - Chicago Policeman
Maudie PrickettHotel maid Elsie
Ned GlassTicket seller
Malcolm AtterburyMan waiting for bus
Bess FlowersPlaza Hotel lounge patron
Stanley AdamsLieutenant Harding (uncredited)
Andy AlbinFarmer (uncredited)
Ernest AndersonPorter on Twentieth Century Ltd. (uncredited)
Tol AveryState Police Detective (uncredited)
Baynes BarronTaxi Driver #2 (uncredited)
Brandon BeachMan at Auction (uncredited)
John BeradinoSergeant Emile Klinger (uncredited)
Steve CarruthersMan at Auction (uncredited)
Taggart CaseyShaving Man (uncredited)
Bill CatchingAuction Attendant (uncredited)
Bill CatchingAuction Attendant (uncredited)
Walter CoyU.S. Intelligence Agency Official (uncredited)
Jimmy CrossTaxi Driver #1 (uncredited)
Patricia CuttsHospital Patient (uncredited)
Jack DalyTrain Steward (uncredited)
John DamlerPolice Lieutenant (uncredited)
Lawrence DobkinU.S. Intelligence Agency Official (uncredited)
Tommy FarrellEddie - Elevator Starter (uncredited)
Jesslyn FaxMinor Role (uncredited)
Adolph FaylauerBald Bidder (uncredited)
Sally FraserSecond United Nations Receptionist (uncredited)
Paul GengeLieutenant Hagerman (uncredited)
James GonzalezMan at Auction (uncredited)
Tom GreenwaySilent State Police Detective (uncredited)
Robert HainesMan at United Nations Building (uncredited)
Stuart HallTrain Passenger (uncredited)
Alfred HitchcockMan Who Misses Bus (uncredited)
Stuart HolmesHotel Lounge Patron (uncredited)
Eugene JacksonSecurity Guard at Auction (uncredited)
Bobby JohnsonWaiter (uncredited)
Kenner G. KempMan Leaving Office Building (uncredited)
Madge KennedyMrs. Finlay (uncredited)
Colin KennyMan at Auction (uncredited)
Carl M. LevinessMan at United Nations Building (uncredited)
Alexander LockwoodJudge Anson B. Flynn (uncredited)
Frank MarloweTaxi Driver (uncredited)
Thomas MartinTrain Passenger (uncredited)
James McCallionPlaza Valet (uncredited)
Maura McGiveneyAttendant (uncredited)
Carl MilletaireHotel Clerk (uncredited)
Hans MoebusMan at United Nations Building (uncredited)
Howard NegleyConductor on Twentieth Century, Ltd. (uncredited)
Monty O'GradyMan at United Nations Building (uncredited)
Ralph ReedBellhop (uncredited)
John RoyTrain Passenger (uncredited)
Jeffrey SayreHotel Lounge Patron / Man at Mt. Rushmore Cafeteria (uncredited)
Scott SeatonMan at Auction (uncredited)
Harry SeymourVictor - Captain of Waiters (uncredited)
Robert ShayneLarry Wade (uncredited)
Jeremy SlatePoliceman at Grand Central Station (uncredited)
Olan SouleAssistant Auctioneer (uncredited)
Helen SpringBidder (uncredited)
Harvey StephensStockbroker (uncredited)
Harry StrangAssistant Conductor (uncredited)
Arthur ToveyMan at Auction (uncredited)
Dale Van SickelRanger (uncredited)
Frank WilcoxHerman Weitner (uncredited)
Lloyd WilliamsMinor Role (uncredited)
Robert WilliamsPatrolman Waggoner (uncredited)
Paula WinsloweWoman at Auction (uncredited)
Wilson WoodPhotographer at United Nations (uncredited)
Carleton YoungFanning Nelson (uncredited)
Dick JohnstoneCourtroom Spectator (uncredited)
Bert StevensMan at United Nations Building (uncredited)
Cosmo SardoWorker (uncredited)
Don AndersonWorker (uncredited)
Alphonso DuBoisMan at United Nations Building (uncredited)
Len HendryPolice Lieutenant (uncredited)
Nora MarloweMenacing housekeeper